• The technology described in this briefing is the AlignRT patient position monitoring system. This briefing focuses on its use during breast cancer radiation therapy.

  • The innovative aspect is that it may avoid inaccurate treatment by precisely tracking a patient's position during radiotherapy and notifying the linear accelerator to hold the radiation beam if the patient moves.

  • The intended place in therapy would be in a standard radiation treatment room with a linear accelerator. It would be used as an alternative to existing patient location monitoring systems using X‑ray/CT and as an adjunct to radiographer visual monitoring of patient movement.

  • The main points from the evidence summarised in this briefing are from 4 observational studies involving a total of 228 adults in tertiary care settings in the US and Europe. They suggest that AlignRT is effective in maintaining accurate patient positioning during breast cancer radiotherapy.

  • Key uncertainties are that there is no evidence from direct comparisons of AlignRT with location monitoring or from studies specifically using AlignRT as the main intervention.

  • The cost of AlignRT is £150,000 to £225,000 per unit (excluding VAT), plus a yearly service charge of £20,000. The cost per treatment will depend on the throughput per device for the variety of radiotherapy procedures the device can be used for.