• The technology described in this briefing is the pCONUS2 Bifurcation Aneurysm Implant. It is used for assisting in the coil occlusion of wide-necked aneurysms that span the division of an artery into 2 branches.

  • The innovative aspects are that the implant has a less than 5% metal to artery surface ratio and can be used without dual antiplatelet treatment.

  • The intended place in therapy would be as an alternative to standard care in people with complex intracranial aneurysms.

  • The main points from the evidence summarised in this briefing are from 1 case series study including a total of 12 adults in secondary care. They show that pCONUS2 is safe and effective at assisting the coil occlusion of an intracranial aneurysm.

  • Key uncertainties around the evidence or technology are that the evidence is from a case series of only 12 patients. There are no comparative studies evaluating its efficacy against standard care.

  • The cost of pCONUS2 is £6,760.00 per unit (excluding VAT), or £7,774.00 per unit with the hydropolymer coating (excluding VAT).