• The technology described in this briefing is the microINR. It is used for measuring international normalised ratio (INR) levels for people having anticoagulation therapy.

  • The innovative aspects are that the device offers portable self-monitoring for coagulation with reduced blood sample needs and increased connectivity capabilities.

  • The intended place in therapy would be as an alternative to hospital‑based testing and alongside alternative point-of-care tests in people who need INR monitoring.

  • NICE's diagnostics guidance on atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers looks at using other INR monitoring devices for anticoagulation therapy.

  • The main points from the evidence summarised in this briefing are from 5 observational comparative studies including a total of 906 adults across primary and secondary care settings. They show that microINR can be as effective as laboratory-based and alternative point-of-care meters in INR monitoring.

  • Key uncertainties around the evidence are that 1 study did not meet the accuracy criteria and 1 study did not meet the imprecision criteria. No studies were done in the UK.

  • The cost of microINR meters range from £299 to £470 per unit (excluding VAT) and microINR chips (disposable test strips) cost between £2.76 and £2.99 per strip; variations seen reflect different distributors. Standard care is alternative point-of-care tests which range from £299 to £590 (excluding VAT) with comparable consumable costs of £2.71 to £3.10 (excluding VAT) per test strip.