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    Endoscopic duodenal mucosal resurfacing for insulin resistance in type 2 diabetes

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    Description:

    Type 2 diabetes can occur when the cells in the body do not respond properly to insulin (insulin resistance). The duodenum (the first part of the small intestine) plays an important role in insulin sensitivity and the regulation of blood sugar. One factor thought to contribute to insulin resistance is the duodenum not working properly.

    In this procedure, an endoscope (a long, thin, flexible tube with a small camera and light on the end) is passed through the mouth into the second section of the duodenum. A balloon catheter is passed through the endoscope and inflated to expand the duodenal mucosa (lining). Then heat is used to destroy the lining. This encourages a new lining to grow (resurfacing). The aim is to make the duodenum work better by making the mucosa more sensitive (less resistant) to insulin.