2 Information about talquetamab

Marketing authorisation indication

2.1

Talquetamab (Talvey, Johnson & Johnson Innovative Medicine) is indicated 'as monotherapy for the treatment of adult patients with relapsed and refractory multiple myeloma, who have received at least 3 prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti‑CD38 antibody and have demonstrated disease progression on the last therapy'.

Dosage in the marketing authorisation

Price

2.3

The list price for talquetamab is £326.41 per 3‑mg vial and £4,352.00 per 40‑mg vial (excluding VAT, BNF online accessed October 2025).

2.4

The company has a commercial arrangement. This makes talquetamab available to the NHS with a discount. The size of the discount is commercial in confidence.

Carbon Reduction Plan