This guidance updates and replaces NICE technology appraisal 205 (published in October 2010)

What has NICE said?

NICE recommends eltrombopag as a possible treatment for some adults with chronic immune (idiopathic) thrombocytopenic purpura (which is sometimes shortened to chronic ITP).

Who can have eltrombopag?

You should be able to have eltrombopag if you have had your spleen removed, or if you have not had your spleen removed because you can’t have the operation, only if:

  • your chronic ITP has not improved even though you have tried other available treatments, or
  • you have severe chronic ITP and a high risk of bleeding that needs frequent courses of emergency treatment.

Why has NICE said this?

NICE looks at how well treatments work, and also at how well they work in relation to how much they cost the NHS.

NICE recommended eltrombopag because it is effective and costs less than other treatments available on the NHS.

Your responsibility

The recommendations in this guidance represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance fully into account, alongside the individual needs, preferences and values of their patients. The application of the recommendations in this guidance is at the discretion of health professionals and their individual patients and do not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.

Commissioners and/or providers have a responsibility to provide the funding required to enable the guidance to be applied when individual health professionals and their patients wish to use it, in accordance with the NHS Constitution. They should do so in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities.

Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible.

  • National Institute for Health and Care Excellence (NICE)