July 2019: Because of a risk of abuse and dependence, pregabalin is controlled under the Misuse of Drugs Act 1971 as a class C substance and scheduled under the Misuse of Drugs Regulations 2001 as schedule 3 (as of 1 April 2019). A footnote has been added in this guideline to reflect this change. Recommendation 1.4.39 was also amended to remove structured problem solving as a care and management option, as this had been originally included in error.
Minor updates since publication
June 2018: Recommendation 1.2.13 was amended with advice on cognitive behavioural therapy (CBT) to bring it in line with current best practice and other NICE guidance. Recommendation 1.2.26 was updated with a link to the newest evidence on use of antipsychotics for treatment of generalized anxiety disorder. Recommendation 1.4.7 was added to give a link to existing guidance on identifying treatment options for common mental health problems. Recommendation 1.4.10 on low-intensity interventions for mild to moderate panic disorder and 1.4.13 on treatment for moderate to severe panic disorder were added, taken from the NICE guideline on common mental health problems. Recommendations in section 1.4 on stepped care for people with panic disorder were reordered.