Information for the public

Drug treatment

Some treatments may not be suitable for you, depending on your exact circumstances. If you have questions about specific treatments and options, please talk to a member of your healthcare team.

During the course of your treatment it is likely that you will be offered different drugs. Your healthcare professional should discuss with you the possible side effects of the drugs, how they could affect your daily activities and why it is important to take drug treatment regularly.

There are three main aims of drug treatment:

  • to provide immediate relief from the symptoms of angina

  • to prevent future angina attacks

  • to reduce your risk of having a heart attack or stroke.

Providing immediate relief from angina

You should be offered a short-acting nitrate drug called glyceryl trinitrate (GTN) to take if you get an attack of angina. You should also take it before you do something that usually brings on an attack, like physical activity, or going out when it is extremely cold. GTN comes as a spray or a tablet, to be sprayed or placed under the tongue. You may get a headache, flushing or dizziness soon after taking it. If you feel dizzy you should sit down or hold onto something until the feeling passes.

If the first dose doesn't work after 5 minutes, you should take another dose. If the pain has not gone away 5 minutes after taking the second dose, you should call an emergency ambulance.

Preventing future angina attacks

Your healthcare professional will usually offer you another drug to take every day to see whether it is effective in preventing your angina symptoms. This will usually be a drug called a beta blocker or a calcium channel blocker (see box below: 'Drugs for preventing symptoms of angina'). Your healthcare professional will check how you are getting on within two to four weeks of starting treatment, or if your treatment is changed. If your symptoms don't improve or you find the drug causes side effects which are a problem for you, your healthcare professional may change your dose of the drug, or offer you another type of drug instead or a combination of two drugs.

If you are still having symptoms with one or two drugs your healthcare professional will consider whether you need a procedure to help increase blood flow to your heart (see 'Procedures to improve blood flow to the heart'). If you are already waiting for a procedure to help increase blood flow to the heart, or such a procedure is not appropriate for you, your healthcare professional may consider a third drug for you to take.

Drugs for preventing symptoms of angina

You may be offered one or more of the following drugs to help prevent your symptoms of angina:

  • Beta blockers slow down the heart rate and reduce the amount of work the heart has to do.

  • Calcium channel blockers relax the blood vessels, increasing the supply of blood to the heart.

  • Long-acting nitrates widen the blood vessels, improving blood flow to the heart.

  • Ivabradine slows down the heart rate and reduces the amount of work the heart has to do.

  • Nicorandil relaxes the blood vessels, increasing the supply of blood to the heart.

  • Ranolazine improves the heart's use of oxygen.

Your healthcare professional will take into account whether you have any other medical conditions, whether you are unable to take a particular type of drug, your personal preference and the cost when deciding which drug to offer you.

Reducing your risk of cardiovascular disease

Your healthcare professional may also offer you drug treatment to help reduce your risk of cardiovascular disease. This might include 75 mg aspirin each day, unless there are reasons why you cannot take it. Aspirin makes your blood less 'sticky' and less likely to form blood clots. You should also be offered a statin, which is a type of drug to help lower your blood cholesterol, so fatty deposits are less likely to form in your blood vessels. If your blood pressure is high you should also be offered treatment to help lower it. If you have diabetes you may be offered a drug called an angiotensin-converting enzyme (ACE) inhibitor to help your stable angina. If you are already taking an ACE inhibitor for another condition, you should continue to take it.

Questions you might like to ask about drug treatment

  • Can you tell me why you have decided to offer me this particular type of drug?

  • Are there any side effects associated with this drug?

  • How long will I have to take the drug?

  • Might I have problems if I stop taking the drug?

  • What might happen if I forget to take it?

  • How long will the drug take to have an effect?

  • Will the dose be changed? When will I need to come back?

  • What other treatments are available?

  • What might happen if I decide not to take the drug?

  • Is there some written material (like a leaflet) about the drug treatment that I can have?

  • Information Standard