Supplementary information on baseline investigations and monitoring

Supplementary information on baseline investigations and monitoring

Table 1 Baseline investigations and monitoring for children and young people who are prescribed antipsychotic medication (read in conjunction with the BNF, BNFC and SPC)

Baseline investigations before starting antipsychotic medication

Monitor weekly for the first 6 weeks

Monitor at 12 weeks

Monitor every 6 months thereafter

Monitor regularly throughout treatment, and especially during titration

Weight1 (plotted on a growth chart)

Yes

Yes

Yes

Yes

Height1 (plotted on a growth chart)

Yes

Yes

Waist circumference (plotted on a percentile chart)

Yes

Yes

Pulse

Yes

Yes

Yes

Blood pressure (plotted on a percentile chart)

Yes

Yes

Yes

Fasting blood glucose

Yes

Yes

Yes

HbA1c (glycosylated haemoglobin)

Yes

Yes

Yes

Blood lipid profile

Yes

Yes

Yes

Prolactin level

Yes

Yes

Yes

Movement disorders (extrapyramidal symptoms, akathisia, dystonia and tardive dyskinesia)

Yes

Yes2

Nutritional status, diet and level of physical activity

Yes

Yes

The side effects the child or young person is most or least willing to tolerate

Yes

ECG

Yes3

Efficacy

Yes

Side effects

Yes

Adherence

Yes

1 Calculate and document BMI (percentile).

2 Even if no baseline assessment (and at each clinic visit if more frequent).

3 If specified in the SPC for adults and/or children; a physical examination has identified specific cardiovascular risk (such as diagnosis of high blood pressure); there is personal history of cardiovascular disease; there is a family history of cardiovascular disease such as sudden cardiac death or prolonged QT interval; or the child or young person is being admitted as an inpatient.

  • National Institute for Health and Care Excellence (NICE)