November 2016: New recommendations have been added for the assessment and diagnosis of acute chest pain and the assessment and diagnosis of stable chest pain.
These are marked as:
[new 2016] if the evidence has been reviewed and the recommendation has been added or updated
 if the evidence has been reviewed but no change has been made to the recommended action.
Where recommendations end , the evidence has not been reviewed since the original guideline.
We have also made some changes without an evidence review:
some 2010 recommendations have been updated to align with the 2016 recommendations
some recommendations have been updated to clarify the use of high-sensitivity troponin testing
some recommendations have been updated to remove reference to estimate of the likelihood of coronary artery disease
reference to autopsy as a diagnostic criterion has been removed.
These recommendations are marked [2010, amended 2016].
Minor changes since publication
January 2020: The title of the guideline was updated to clarify that it covers chest pain of suspected cardiac origin. A footnote to recommendation 220.127.116.11 was changed to update a link to the universal definition of myocardial infarction, and a cross-reference to related NICE medical technologies guidance was added at the end of section 1.3.4.