Entrectinib for treating NTRK fusion-positive solid tumours in people 12 years and over (terminated appraisal) (TA1118)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 7 January 2026
Cemiplimab with platinum-based chemotherapy for untreated advanced non-small-cell lung cancer (TA1108)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 5 November 2025
Lorlatinib for ALK-positive advanced non-small-cell lung cancer that has not been treated with an ALK inhibitor (TA1103)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 21 October 2025
Durvalumab for treating limited-stage small-cell lung cancer after platinum-based chemoradiotherapy (TA1099)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 1 October 2025
Tarlatamab for extensive-stage small-cell lung cancer after 2 or more treatments (TA1091)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 20 August 2025
Amivantamab with lazertinib for untreated EGFR mutation-positive advanced non-small-cell lung cancer [ID6256]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 21 January 2026
Nivolumab as neoadjuvant (with chemotherapy) and adjuvant (as monotherapy) treatment for resectable non-small-cell lung cancer [ID6310]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 4 February 2026
Suspected Cancer: recognition and referral (update)Status:In development | In consultationProgramme:NICE guidelineConsultation end date: 2 February 2026Expected publication date: 25 March 2026
Osimertinib for maintenance treatment of EGFR mutation-positive locally advanced unresectable non-small-cell lung cancer after platinum-based chemoradiation [ID6223]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 8 April 2026
Larotrectinib for treating NTRK fusion-positive advanced solid tumours (MA review of TA630) [ID6292]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: 21 May 2026
Catumaxomab for intraperitoneal treatment of malignant ascites in epithelial cellular adhesion molecule-positive carcinomas when further systemic anticancer treatment is unsuitable [ID6580]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 30 September 2026
Lurbinectedin with atezolizumab for maintenance treatment of extensive-stage small-cell lung cancer [ID6526]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 2 December 2026
Durvalumab with radiotherapy for treating unresected node-negative stage 1 or 2 non-small-cell lung cancer [ID6567]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 14 April 2027
Atezolizumab as neoadjuvant (with chemotherapy) and adjuvant (as monotherapy) treatment for resectable non-small-cell lung cancer [ID3894]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Amivantamab with carboplatin and pemetrexed for untreated EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer [ID5110]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tislelizumab with platinum-based chemotherapy and etoposide for untreated extensive-stage small-cell lung cancer [ID6158]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Encorafenib with binimetinib for treating BRAF V600E mutation-positive advanced non-small-cell lung cancer [ID6177]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Durvalumab with tremelimumab for treating limited-stage small-cell lung cancer after chemoradiation [ID5097]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tiragolumab with atezolizumab for treating locally advanced unresectable stage 3 non-small-cell lung cancer after at least 2 cycles of platinum-based chemoradiation [ID6250]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Serplulimab with carboplatin and etoposide for untreated extensive-stage small-cell lung cancer [ID6346]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sotorasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (MA review of TA781) [ID6287]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Cobolimab with dostarlimab and docetaxel for treating advanced non-small-cell lung cancer after anti-PD-L1 treatment and chemotherapy [ID6398]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Patritumab deruxtecan for treating EGFR mutation-positive advanced non-small-cell lung cancer after 1 or 2 tyrosine kinase inhibitor treatment [ID6467]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Osimertinib for neoadjuvant treatment of EGFR mutation-positive resectable non-small-cell lung cancer [ID6472]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Savolitinib with osimertinib for treating EGFR-mutated MET-overexpressed or amplified advanced non-small-cell lung cancer after osimertinib [ID6494]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Zongertinib for treating HER2-mutated unresectable or metastatic non-small-cell lung cancer [ID6573]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Ceralasertib with durvalumab for treating advanced non-small-cell lung cancer after antiPD-L1 treatment and platinum-based chemotherapy [ID6612]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tarlatamamb for treating extensive stage small-cell lung cancer that has progressed after platinum-based chemotherapy [ID6617]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sevabertinib for untreated HER2-positive advanced non-small-cell lung cancer [ID6616]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Durvalumab with oleclumab or monalizumab for treating unresectable locally advanced non-small-cell lung cancer after platinum-based chemoradiotherapy [ID6626]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Trilaciclib for preventing myelosuppression caused by chemotherapy for extensive-stage small-cell lung cancer [ID6651]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sacituzumab govitecan with pembrolizumab for untreated metastatic non-small-cell lung cancer with a PD-L1 expression of 50% or more [TSID12280]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC