Suggested remit: To appraise the clinical and cost-effectiveness of catumaxomab within its marketing authorisation for treating malignant ascites in epithelial cellular adhesion molecule-positive carcinomas when further systemic anticancer treatment is unsuitable.

Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6580

Provisional Schedule

Committee meeting:
10 June 2026
Expected publication:
30 September 2026

Project Team

Project lead
Kate Moore

Email enquiries

If you have any queries please email TACommD@nice.org.uk


External Assessment Group:
Warwick Evidence, Warwick Medical School, University of Warwick

Stakeholders

Companies sponsors
Pharmanovia (catumaxomab)
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
AMEND
 
AMMF – The Cholangiocarcinoma Charity
 
Black Health Agency for Equality
 
Bob Champion Cancer Trust
 
Bowel Cancer UK
 
Breast Cancer Now
 
Breast Cancer UK
 
British liver Trust
 
Butterfly Thyroid Cancer Trust
 
Cancer Black Care
 
Cancer52
 
Eve Appeal
 
Fight Bladder Cancer
 
GIST Cancer UK
 
Go Girls
 
Guts UK
 
Helen Rollason Cancer Charity
 
Independent Cancer Patients Voice
 
Inflammatory Breast Cancer Network UK
 
Liver4Life
 
LIVErNORTH
 
Lobular Breast Cancer
 
Macmillan Cancer Support
 
Maggie’s Centres
 
Marie Curie
 
METUPUK
 
OG Support
 
OPA Cancer Charity Oesophageal and Gastric Support
 
Oncogene-Driven Lung Cancer Patient Alliance UK
 
Oncogene Cancer Research
 
Orchid
 
Ovacome
 
Ovarian Cancer Action
 
Pancreatic Cancer Action
 
Pancreatic Cancer UK
 
PCaSO Prostate Cancer Support Organisation
 
Pelican Cancer Foundation
 
Prevent Breast Cancer
 
Prostate Cancer Research
 
Prostate Matters
 
Robin Cancer Trust
 
Roy Casle Lung Cancer Foundation
 
South Asian Health Foundation
 
Specialised Healthcare Alliance
 
Tackle Prostate Cancer
 
Target Ovarian Cancer
 
Tenovus Cancer Care
 
United Kingdom Lung Cancer Coalition
Professional groups
Association of Cancer Physicians
 
British Geriatrics Society
 
British Oncology Pharmacy Association
 
British Psychosocial Oncology Society
 
Cancer Research UK
 
Cholangiocarcinoma UK
 
Royal College of General Practitioners
 
Royal College of Nursing
 
Royal College of Pathologists
 
Royal College of Physicians
 
Royal Pharmaceutical Society
 
Royal Society of Medicine
 
UK Clinical Pharmacy Association
 
UK Oncology Nursing Society
Associated public health groups
Public Health Wales
 
UK Health Security Agency
Comparator companies
None
General commentators
All Wales Therapeutics and Toxicology Centre
 
Allied Health Professionals Federation
 
Board of Community Health Councils in Wales
 
British National Formulary
 
Care Quality Commission
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
National Association of Primary Care
 
National Pharmacy Association
 
NHS Confederation
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government
Relevant research groups
Genomics England
 
Institute of Cancer Research
 
MRC Clinical Trials Unit
 
National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
28 October 2025 Invitation to participate
02 October 2025 To appraise the clinical and cost effectiveness of Catumaxomab within its marketing authorisation for treating malignant ascites ID6580
25 July 2025 - 22 August 2025 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 6580
25 July 2025 In progress. Scoping commencing
15 May 2025 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual