Tools and resources

4 Tips for adopting high-throughput NIPT for fetal RHD genotype

4 Tips for adopting high-throughput NIPT for fetal RHD genotype

The NHS contributors to this resource considered the following to be important:

  • Consider whether a pilot period is appropriate.

  • If the pregnant women in the population are known to move across geographical health boundaries, the potential benefits of joint implementation with neighbouring organisations should be assessed.

  • Establish who is responsible for ordering, stocking, issuing, funding and the contractual arrangements for anti‑D immunoglobulin. Review the annual contract for anti‑D procurement to avoid over ordering and waste (see assessment of readiness).

  • Assess the interoperability of the:

  • Complete a resource impact assessment to see if local implementation will be cost effective as outlined in the NICE guidance (see resource impact).

  • Identify how the service will be measured in terms of quality and safety, patient experience, productivity and improved clinical outcomes. Consider what baseline assessment will be used and how to monitor uptake of the test (see measuring success).

  • Develop and prioritise a staged training plan for the various staff groups (see education and communication plans).

  • Develop a staged communication plan to raise awareness among staff and patients before implementation and again before the time of delivery (see education and communication plans).

  • Include a flowchart in the protocols and local guidelines (see develop local documentation).


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