Following on from information provided to NICE by the company in May 2018, the appraisal of Idelalisib with bendamustine and rituximab for previously treated chronic lymphocytic leukaemia [ID839] was suspended from NICE’s work programme. As no further information has been received from the company the topic has been discontinued.

Status:
Discontinued
Technology type:
Medicine
Decision:
Prioritised
Process:
TA
ID number:
839

Email enquiries

If you have any queries please email scheduling@nice.org.uk

Stakeholders

Companies sponsors
Gilead Sciences (idelalisib)
Others
Department of Health
 
NHS England
 
Welsh Government
Patient carer groups
Leukaemia CARE
Professional groups
Association of Cancer Physicians
 
Cancer Research UK
 
Royal College of Physicians
 
Royal College of Radiologists
Comparator companies
Accord Healthcare (fludarabine) (not participating, confidentiality agreement not signed)
 
Actavis (fludarabine) (not participating, confidentiality agreement not signed)
 
Allergan (fludarabine) (not participating, confidentiality agreement not signed)
 
Aspen Pharma (chlorambucil) (not participating, confidentiality agreement not signed)
 
Baxter Healthcare (cyclophosphamide) (not participating, confidentiality agreement not signed)
 
Genzyme (fludarabine) (not participating, confidentiality agreement not signed)
 
GlaxoSmithKline (chlorambucil,) (not participating, confidentiality agreement not signed)
 
Hospira UK (fludarabine) (not participating, confidentiality agreement not signed)
 
Janssen (ibrutinib)
 
Pfizer (cyclophosphamide)
 
Roche Products (rituximab) (not participating, confidentiality agreement not signed)
 
Sandoz (cyclophosphamide) (not participating, confidentiality agreement not signed)
 
Sanofi (fludarabine) (not participating, confidentiality agreement not signed)
 
Teva UK (fludarabine) (not participating, confidentiality agreement not signed)
General commentators
All Wales Therapeutics and Toxicology Centre
 
British National Formulary
 
Department of Health, Social Services and Public Safety for Northern Ireland
 
Healthcare Improvement Scotland
 
Welsh Health Specialised Services Committee
Relevant research groups
Institute of Cancer Research
 
National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
31 October 2022 Note added to the project documents
31 October 2022 Discontinued. Following on from information provided to NICE by the company in May 2018, the appraisal of Idelalisib with bendamustine and rituximab for previously treated chronic lymphocytic leukaemia [ID839] was suspended from NICE’s work programme. As no further information has been received from the company the topic has been discontinued.
10 May 2018 Note added to the project documents
03 May 2017 Suspended. This appraisal has formally started now, in line with the anticipated regulatory timelines. However, the Gilead has informed us that they will not provide an evidence submission for this appraisal. NICE will therefore suspend this appraisal with immediate effect.
03 May 2017 Invitation to participate
08 June 2016 Referral

For further information on our processes and methods, please see our CHTE processes and methods manual