Suggested remit: To appraise the clinical and cost effectiveness of benralizumab within its marketing authorisation for previously treated severe nasal polyps.

Following on from information provided to NICE by the company in March 2025, the appraisal of Benralizumab with mometasone furoate for treating severe nasal polyps [ID1659] was suspended from NICE’s work programme. As no further information has been received from the company the topic has been discontinued.

Status:
Discontinued
Decision:
Prioritised
Process:
TA
ID number:
1659

Email enquiries

If you have any queries please email scopingta@nice.org.uk

Timeline

Key events during the development of the guidance:

Date Update
22 April 2026 Discontinued. Following on from information provided to NICE by the company in March 2025, the appraisal of Benralizumab with mometasone furoate for treating severe nasal polyps [ID1659] was suspended from NICE’s work programme. As no further information has been received from the company the topic has been discontinued.
01 April 2025 Suspended. As you will be aware, the Department for Health & Social Care has asked NICE to carry out a Single Technology Appraisal of Benralizumab with mometasone furoate for treating severe nasal polyps. For information, the company have advised that they are no longer pursuing a Marketing Authorisation Application from the Medicines and Healthcare products Regulatory Agency (MHRA) for this indication at this time. Therefore, NICE has decided to suspend this appraisal from its current work programme. As this appraisal has been referred NICE will continue to monitor any development and will update interested parties if the situation changes.
05 August 2024 Note - Note added to the project documents
16 March 2021 Note added to the project documents

For further information on our processes and methods, please see our CHTE processes and methods manual