2.1
Varicose veins are a sign of underlying venous insufficiency and affect 20% to 30% of adults. Most people with varicose veins have no symptoms but venous insufficiency may cause fatigue, heaviness, aching, throbbing, itching and cramps in the legs. Chronic venous insufficiency can lead to skin discoloration, inflammatory dermatitis and ulceration. Great saphenous vein insufficiency is the most common form of venous insufficiency in people presenting with symptoms.