Overview

Evidence-based recommendations on biomarker tests to help diagnose preterm labour in women with intact membranes. The tests are Actim Partus, PartoSure and the Rapid fetal fibronectin (fFN) 10Q Cassette Kit (at thresholds other than 50 nanograms/millilitre).

 November 2024: There is a problem with the supply of cassettes used for fetal fibronectin testing. We will review our guidance and use our topic prioritisation process to decide whether to update it. For more information, see the NHS England letter on the discontinuation of Hologic fetal fibronectin testing.

Last reviewed: 4 July 2018

Diagnostics guidance 33 has been migrated to HealthTech guidance 476. The recommendations and accompanying content remain unchanged.

Next review: This guidance will be reviewed if there is new evidence that is likely to change the recommendations.

Guidance development process

How we develop NICE HealthTech guidance