3.1
NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 8 sources, which was discussed by the committee. The evidence included 1 systematic review and network meta-analysis, 3 randomised controlled trials, 2 non-randomised comparative studies and 1 case series. The committee also considered safety data from 3 implant summary reports for the Profemur L Modular Stem, Profemur L Classic Stem and Procotyl L Cup, provided by the National Joint Registry. It is presented in the summary of key evidence section in the overview. Other relevant literature is in the appendix of the overview.