Update information

September 2023: The evidence generation plan gives further information on the prioritised evidence gaps and outcomes, ongoing studies and potential real-world data sources. It includes how the evidence gaps could be resolved through real-world evidence studies.

Minor changes since publication

December 2025: Health technology evaluation 3 has been migrated to HealthTech guidance 660. The recommendations and accompanying content remain unchanged

October 2023: We updated the equality sections in 1.1 and 3.5 to clarify the population.

ISBN: 978-1-4731-7758-1