This is an update to NICE guideline NG217 (published April 2022 and previously updated January 2025).

We are reviewing recommendations 6.4.2 to 6.4.4 in section 6.4 on self-limited epilepsy with centrotemporal spikes. We are in the process of:

  • reviewing the licensed status for treatments recommended for self-limited epilepsy with centrotemporal. spikes including the UK licencing approval of sultiame in January 2025.
  • searching for any new evidence on treatments for self-limited epilepsy with centrotemporal spikes.
  • we have appointed an expert working group to advise on any changes to recommendations.
  • we will consult on any proposed changes.

This guidance will partially update the following:

Status:
In progress
Decision:
Awaiting decision
Developed as:
CG
ID number:
1321

Email enquiries

If you have any queries please email Epilepsiescypadults@nice.org.uk

Timeline

Key events during the development of the guidance:

Date Update
01 April 2026 Committee list updated
01 April 2026 Declaration of interests
01 April 2026 Stakeholder list updated

For further information on the guideline development process, please see how we develop NICE guidelines