Suggested remit - To appraise the clinical and cost-effectiveness of acalabrutinib within its marketing authorisation for treating chronic lymphocytic leukaemia
 
Status In progress
Process STA 2018
ID number 1613

Project Team

Project lead Louise Jafferally

Email enquiries

Evidence Review Group / Assessment Group BMJ Technology Assessment Group (BMJ-TAG), BMJ

Consultees

Companies sponsors AstraZeneca (acalabrutinib)
Others Department of Health and Social Care
  NHS England
  NHS South Gloucestershire CCG
  NHS Swale CCG
  Welsh Government
Patient carer groups African Caribbean Leukaemia Trust
  Anthony Nolan
  Black Health Agency
  Bloodwise
  Cancer Black Care
  Cancer Equality
  Cancer52
  Chronic Lymphocytic Leukaemia Support Association
  DKMS
  Helen Rollason Cancer Charity
  Independent Cancer Patients Voice
  Leukaemia Cancer Society
  Leukaemia CARE
  Lymphoma Action
  Macmillan Cancer Support
  Maggie’s Centres
  Marie Curie
  Muslim Council of Britain
  South Asian Health Foundation
  Specialised Healthcare Alliance
  Tenovus Cancer Care
  WMUK
Professional groups Association of Cancer Physicians
  British Blood Transfusion Society
  British Committee for Standards in Haematology
  British Geriatrics Society
  British Institute of Radiology
  British Psychosocial Oncology Society
  British Society for Haematology
  British Society of Interventional Radiology
  Cancer Research UK
  Royal College of General Practitioners
  Royal College of Nursing
  Royal College of Pathologists
  Royal College of Physicians
  Royal College of Radiologists
  Royal Pharmaceutical Society
  Royal Society of Medicine
  Society and College of Radiographers
  UK Chronic Lymphocytic Leukaemia Forum
  UK Clinical Pharmacy Association
  UK Oncology Nursing Society

Commentators

Associated public health groups Public Health England
  Public Health Wales
Comparator companies Abbvie (venetoclax)
  Accord Healthcare (bendamustine, fludarabine)
  Actavis UK (fludarabine)
  AAH Pharmaceuticals (chlorambucil)
  Aspen (chlorambucil)
  Baxter healthcare (cyclophosphamide)
  Dr Reddy’s Laboratories (bendamustine)
  Gilead Sciences (idelalisib)
  Janssen (Ibrutinib)
  medac (bendamustine)
  Napp Pharmaceuticals (bendamustine, rituximab)
  Roche (rituximab, obinutuzumab)
  Sandoz (rituximab, cyclophosphamide, fludarabine)
  Sanofi (fludarabine)
  Seacross Pharmaceuticals (bendamustine)
  Zentiva (bendamustine)
General commentators All Wales Therapeutics and Toxicology Centre
  Allied Health Professionals Federation
  Board of Community Health Councils in Wales
  British National Formulary
  Care Quality Commission
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Hospital Information Services – Jehovah’s Witnesses
  Medicines and Healthcare products Regulatory Agency
  National Association of Primary Care
  National Pharmacy Association
  NHS Alliance
  NHS Blood and Transplant
  NHS Confederation
  Scottish Medicines Consortium
  Welsh Health Specialised Services Committee
Relevant research groups Cochrane Haematological Malignancies Group
  Genomics England
  Institute of Cancer Research
  Leuka
  Leukaemia Busters
  Lymphoma Research Trust
  MRC Clinical Trials Unit
  National Cancer Research Institute
  National Cancer Research Network
  National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
06 March 2020 Invitation to participate
06 March 2020 In progress, In appraisal
09 September 2019 - 04 October 2019 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance