Suggested remit: To appraise the clinical and cost effectiveness of efgartigimod with recombinant human hyaluronidase PH20 within its marketing authorisation for treating chronic inflammatory demyelinating polyneuropathy.

Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6409

Provisional Schedule

Committee meeting:
19 March 2026
Expected publication:
29 July 2026

Project Team

Project lead
Thomas Feist

Email enquiries

If you have any queries please email HST@nice.org.uk


External Assessment Group:
BMJ Technology Assessment Group (BMJ-TAG), BMJ

Stakeholders

Companies sponsors
argenx
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
Guillain-Barré and Associated
 
Inflammatory Neuropathies (GAIN)
Professional groups
Association of British Neurologists
 
Royal College of Physicians
Comparator companies
Grifols UK (human immunoglobulin)
 
Octapharma (human immunoglobulin)
 
Takeda UK (human immunoglobulin)
General commentators
All Wales Therapeutics and Toxicology Centre
 
British National Formulary
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government

Timeline

Key events during the development of the guidance:

Date Update
14 August 2025 Invitation to participate
28 January 2025 Please note that following on from a request received from the company, the timelines for this appraisal have been revised and the appraisal is now anticipated to begin during early August 2025 when we will write to you about how you can get involved.
06 January 2025 (14:00) Scoping workshop
01 November 2024 - 29 November 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 6409
01 November 2024 In progress. Scoping commencing
31 January 2024 Awaiting development. Status change linked to Topic Selection Decision being set to Selected
30 January 2024 Topic selection

For further information on our processes and methods, please see our CHTE processes and methods manual