Guidance
Skip Standards and indicators submenu
Quality standards
Our quality standards set out priority areas for quality improvement. They highlight areas with identified variation in current practice.
View our quality standards
How to use our quality standards
The timeline for developing quality standards
Help us develop quality standards
Selecting and prioritising quality standards topics
About quality standards
Indicators
Our indicators measure outcomes that reflect the quality of care, or processes linked by evidence to improved outcomes.
View list of indicators
Learn about the committee that develops indicators
About indicators
Skip Life sciences submenu
Life Sciences
We offer tailored support to industry during product development. Our expertise can help you build the evidence needed to achieve market access.
View life sciences
Get support from NICE
NICE Advice service
Trusted, unrivalled expertise.
Make an enquiry
Contact us to discuss your requirements.
Innovative Licensing and Access Pathway (ILAP)
Streamlining patient access to safe, financially sustainable and innovative medicines.
Learn how we evaluate technologies
Health technology evaluation and topic selection manuals
Updated manuals for methods, processes and topic selection.
Digital health technologies
Accelerating our efforts to deliver innovation to the health and care system.
Evidence standards framework
Using the best available evidence to develop recommendations that guide decisions in health, public health and social care.
Our guidance programmes
Ensuring new technologies are clinically effective and offer economic value.
Register your product
Non-pharmaceutical
NHS Innovation Service is a clear and simple point of entry for health technologies to access support and national evaluation programmes.
Pharmaceutical
UK PharmaScan is a database of new medicines, indications and formulations in the pharmaceutical pipeline.
Find published and proposed evaluations
Diagnostics
Guidance on measurements and tests used to evaluate a patient's condition.
Medical technologies
Guidance on medical technologies put forward to NICE by manufacturers.
Technology appraisals
Guidance on new and existing medicines and treatments in the NHS.
Highly specialised technologies
Guidance on the use of highly specialised medicines and treatments.
British National Formulary (BNF)
British National Formulary for Children (BNFC)
Clinical Knowledge Summaries (CKS)
Skip About submenu
About
NICE helps practitioners and commissioners get the best care to patients, fast, while ensuring value for the taxpayer.
Explore about
Our programmes
Learn about the information we produce.
Guidance
Advice
Quality standards
Indicators
Digital health
Topic selection
Get involved
Understand how decisions are made:
Attend a committee meeting
Comment on draft guidance:
Guidance in consultation
Be part of a guidance committee:
Join a committee
Help develop our products:
Register as a stakeholder
Putting you at the heart of our work:
Public involvement
What we do
Social care
Life sciences
NICE international
Patient safety
Shared decision making
View all What we do
Into practice
Social care quick guides
Measuring the use of NICE guidance
Resource planner
View all Into practice
Who we are
The board
The NICE strategy 2021 to 2026
Corporate publications
View all Who we are
- Contact us
- Jobs

Ibrutinib for previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia with 17p deletion or TP53 mutation

Technology appraisal guidance
Reference number: TA429
Published: 25 January 2017

History

Final appraisal determination

Final appraisal determination
Final appraisal determination document (PDF 463 KB)

Published:

25 November 2016
Committee papers (PDF 1.07 MB)

Published:

25 November 2016
Committee papers (PDF 883 KB)

Published:

25 November 2016

Draft guidance: 2

Draft guidance: 2
Appraisal consultation document (PDF 513 KB)

Published:

01 June 2016
Committee papers (PDF 1.57 MB)

Published:

01 June 2016

Draft guidance

Draft guidance
Committee papers (PDF 6.16 MB)

Published:

02 March 2016
Appraisal consultation document (PDF 515 KB)

Published:

26 April 2016

Invitation to participate

Equality impact assessment (Scoping) (PDF 73 KB)

Published:

23 December 2015

Final scope

Final scope
Final scope (PDF 87 KB)

Published:

15 September 2015

Final matrix

Final matrix
Final matrix (PDF 90 KB)

Published:

15 September 2015

Comments table

Comments table
Comments table (PDF 132 KB)

Published:

15 September 2015

Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (post-referral) - July 2015

Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (post-referral) - July 2015
Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (post-referral) - July 2015 (PDF 91 KB)

Published:

22 July 2015

Leukaemia (chronic lymphocytic) - ibrutinib: draft scope for consultation (post-referral) - July 2015

Leukaemia (chronic lymphocytic) - ibrutinib: draft scope for consultation (post-referral) - July 2015
Leukaemia (chronic lymphocytic) - ibrutinib: draft scope for consultation (post-referral) - July 2015 (PDF 93 KB)

Published:

22 July 2015

Leukaemia (chronic lymphocytic) - ibrutinib: draft scope (pre-referral) - June 2014

Leukaemia (chronic lymphocytic) - ibrutinib: draft scope (pre-referral) - June 2014
Leukaemia (chronic lymphocytic) - ibrutinib: draft scope (pre-referral) - June 2014 (PDF 106 KB)

Published:

12 December 2014

Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (pre-referral) - June 2014

Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (pre-referral) - June 2014
Leukaemia (chronic lymphocytic) - ibrutinib: provisional matrix (pre-referral) - June 2014 (PDF 102 KB)

Published:

12 December 2014