1 Recommendations

1 Recommendations

1.1 Current evidence on the efficacy and safety of faecal microbiota transplant for recurrent Clostridium difficile infection is adequate to support the use of this procedure provided that normal arrangements are in place for clinical governance, consent and audit.

1.2 This procedure should only be considered for patients with recurrent C. difficile infections that have failed to respond to antibiotics and other treatments.

1.3 Clinicians should ensure that a confidential record is kept of the donor and recipient of each faecal microbiota transplant.

1.4 NICE encourages further research into faecal microbiota transplant for C. difficile infection, specifically to investigate optimal dosage, mode of administration and choice of donor.

  • National Institute for Health and Care Excellence (NICE)