2 Indications and current treatments
2.1 Symptomatic interdigital (Morton's) neuroma is caused by perineural fibrosis which creates scar tissue, resulting in compression of an interdigital nerve. It usually occurs between the metatarsal heads of the third and fourth toes but can sometimes occur between the second and third toes. Symptoms include severe intermittent pain, a burning sensation, and paraesthesia in the front part of the sole of the foot, extending into the toes.
2.2 Initial management of symptomatic Morton's neuroma includes rest, anti‑inflammatory medications, using an orthosis in the shoe and wearing a different type of shoe. Injection of steroids and local anaesthetic may be used. Persistent symptoms may be treated by cryoablation or surgical removal of the nerve (neurectomy).