Endoscopic full thickness removal of non-lifting colonic polyps

4 Efficacy

This section describes efficacy outcomes from the published literature that the committee considered as part of the evidence about this procedure. For more detailed information on the evidence, see the interventional procedure overview.

4.1 In a case series of 25 patients treated by endoscopic full thickness removal (EFTR) for colonic polyps, there was technical success in 83% (20/24). In a case series of 17 patients (10 with colonic lesions) treated by EFTR, there was technical success in 90% (9/10).

4.2 In the case series of 25 patients, there was complete resection (no microscopic residual tumour) in 75% (18/24). In the same study, residual polyps were present in 16% (4/25) of patients. In the case series of 17 patients, there was complete resection in 100% (9/9) of those with colonic lesions.

4.3 In the case series of 25 patients, there was full thickness resection of the lesion in 88% (21/24). In the case series of 17 patients, there was full thickness resection in 100% (9/9) of those with colonic lesions.

4.4 In the case series of 25 patients, local recurrence of the lesion at follow‑up was reported in 4% (1/25).

4.5 The specialist advisers listed the following efficacy outcomes: histological confirmation of complete removal of the lesion, successful full thickness resection, avoidance of surgery, standardised reporting of lesion histology and documented audit of complications.