1 Recommendations

1 Recommendations

1.1 Current evidence on platelet-rich plasma injections for knee osteoarthritis raises no major safety concerns. However, the evidence on efficacy is limited in quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research.Find out what special arrangements mean on the NICE interventional procedures guidance page.

1.2 Clinicians wishing to give platelet-rich plasma injections for knee osteoarthritis should:

1.3 Further research should be in the form of randomised controlled trials with medium- to long-term follow‑up, including validated measures of knee function and patient-reported outcomes.

  • National Institute for Health and Care Excellence (NICE)