3.1 NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 10 sources, which was discussed by the committee. The evidence included 1 meta-analysis, 8 case series and 1 case report. It is presented in table 2 of the interventional procedures overview. Other relevant literature is in the appendix of the overview.
3.2 The professional experts and the committee considered the key efficacy outcomes to be: weight loss in the short term, maintenance of weight loss in the long term, and improved comorbidities and quality of life.
3.3 The professional experts and the committee considered the key safety outcomes to be: gastrointestinal obstruction, perforation, early balloon deflation and expulsion.
3.4 Three commentaries from patients who have had this procedure were discussed by the committee.
3.5 The procedure may be useful for people who need to lose weight rapidly before surgery or other procedures.
3.6 The committee noted that nausea and vomiting were associated with this procedure, as with other intragastric balloon procedures.
3.7 The committee was informed that the technology is evolving.