Recommendations for research

Recommendations for research

The guideline committee has made the following recommendations for research.

Key recommendations for research

1 Surgery to the breast

What is the optimum tumour‑free margin width after breast‑conserving surgery for women with ductal carcinoma in situ (DCIS) and invasive breast cancer?

To find out why the committee made the research recommendation on surgery to the breast, see rationale and impact.

2 Adjuvant bisphosphonate therapy

Which groups of people with early and locally advanced breast cancer would benefit from the use of adjuvant bisphosphonates?

To find out why the committee made the research recommendation on bisphosphonates, see rationale and impact.

3 Breast reconstruction

What are the long‑term outcomes for breast reconstruction in women having radiotherapy to the chest wall?

To find out why the committee made the research recommendation on postmastectomy radiotherapy, see rationale and impact.

4 Neoadjuvant endocrine therapy in premenopausal women

Is neoadjuvant endocrine therapy safe in premenopausal women with early breast cancer?

To find out why the committee made the research recommendation on neoadjuvant endocrine therapy in premenopausal women, see rationale and impact.

5 Neoadjuvant endocrine therapy in postmenopausal women

Is there a benefit for neoadjuvant endocrine therapy in postmenopausal women with early breast cancer?

To find out why the committee made the research recommendation on neoadjuvant endocrine therapy in postmenopausal women, see rationale and impact.

6 Neoadjuvant treatment

What are the indications for postmastectomy radiotherapy after neoadjuvant chemotherapy?

To find out why the committee made the research recommendation on neoadjuvant treatment, see rationale and impact.

  • National Institute for Health and Care Excellence (NICE)