Other considerations

Medicines adherence

Medicines adherence may be a problem for some people with medicines that require regular dosing or longer treatment duration (for example, continuous antibiotic prophylaxis). See the NICE guideline on medicines adherence.

Resource implications

Recommended antibiotics are available as generic formulations, see the Drug Tariff for costs.

Nitrofurantoin 25 mg/5 ml oral suspension is more expensive than other oral suspensions, such as trimethoprim 50 mg/5 ml. The cost of a 300‑ml bottle of nitrofurantoin is £446.95 compared with £4.87 for a 100‑ml bottle of trimethoprim (Drug Tariff, September 2018).

  • National Institute for Health and Care Excellence (NICE)