Recommendations for research

The 2019 guideline committee has made the following recommendation for research.

Recommendations for research from the 2019 guideline

1 Enteral nutrition after surgery

What are the benefits, risk and cost effectiveness of enteral nutrition in maintaining remission in the post-surgical period of Crohn's disease?

For a short explanation of why the committee made the recommendation for research, see the rationale on maintaining remission in Crohn's disease after surgery.

Full details of the evidence and the committee's discussion are in the evidence review: Crohn's disease management – post surgical maintenance of remission.

Other recommendations for research from the 2012 guideline

2 Azathioprine

Does the addition of azathioprine to systemic glucocorticosteroid treatment at diagnosis improve the long-term outcome compared with glucocorticosteroid treatment alone for patients with intestinal Crohn's disease?

3 Mesalazine

Following successful medical induction of remission of Crohn's disease of the colon, is mesalazine more clinically and cost effective than no treatment?

4 Distal ileum

What is the effect on quality of life of medical treatment compared with early surgery for Crohn's disease limited to the distal ileum?

5 Enteral nutrition compared to glucocorticosteroid treatment

What are the benefits, risks and cost effectiveness of enteral nutrition compared to glucocorticosteroid treatment in adults, children and young people?

6 Information needs

What are the information needs of people with Crohn's disease, as defined by people with the condition, and can education and support based on these needs lead to better clinical and quality-of-life outcomes?