Recommendations for research

The guideline committee has made the following recommendations for research.

Key recommendations for research

1 Diagnostic tests

What diagnostic tests are clinically and cost effective in people with suspected myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome (ME/CFS)?

For a short explanation of why the committee made this recommendation, see the rationale section on suspecting ME/CFS.

Full details of the evidence and the committee's discussion are in evidence review D: identifying and diagnosing ME/CFS.

2 A core outcome set

What core set of relevant health outcome measures should be used for trials of treatments for ME/CFS and managing symptoms of ME/CFS?

For a short explanation of why the committee made this recommendation, see the rationale section on managing ME/CFS.

Full details of the evidence and the committee's discussion are in evidence review G: non-pharmacological management of ME/CFS.

3 Diagnostic criteria

In people with suspected ME/CFS, how effective is the NICE 2021 consensus-based diagnostic criteria in identifying people with ME/CFS?

For a short explanation of why the committee made this recommendation, see the rationale section on suspecting ME/CFS.

Full details of the evidence and the committee's discussion are in evidence review D: identifying and diagnosing ME/CFS.

Other recommendations for research

Self-monitoring management strategies

What is the clinical and cost effectiveness of self-monitoring strategies and techniques in guiding energy management?

For a short explanation of why the committee made this recommendation, see the rationale section on energy management.

Full details of the evidence and the committee's discussion are in evidence review G: non-pharmacological management of ME/CFS.

Sleep management strategies

What is the clinical and cost effectiveness of sleep management strategies in managing ME/CFS?

For a short explanation of why the committee made this recommendation, see the rationale section on rest and sleep.

Full details of the evidence and the committee's discussion are in evidence review G: non-pharmacological management of ME/CFS.

Dietary strategies

What is the clinical and cost effectiveness of dietary strategies in managing ME/CFS?

For a short explanation of why the committee made this recommendation, see the rationale section on dietary management and strategies.

Full details of the evidence and the committee's discussion are in evidence review G: non-pharmacological management of ME/CFS.

  • National Institute for Health and Care Excellence (NICE)