August 2019: We have reviewed the evidence and made new recommendations on the effectiveness of prophylactic vaginal progesterone and prophylactic cervical cerclage for preterm labour and birth. These recommendations are marked .
We have also made some changes without an evidence review:
updated recommendations to show cervical length of 25 mm or less as indicative of a high risk of preterm birth for consistency
updated licensing information for erythromycin and magnesium sulfate use during pregnancy
updated the time period when corticosteroids are offered to women with suspected preterm labour reflect current practice
updated advice on insulin-like growth factor binding protein 1 test or placental alpha-microglobulin 1 testing in preterm rupture of membranes to remove the word 'consider', making it clearer when the tests should be used.
These recommendations are marked [2015, amended 2019].
Minor changes since publication
October 2019: The review date for recommendation 1.3.1 was updated to show it had been amended in 2019 without an evidence review.