Evaluating risk level

For people who are or have recently been pregnant, NICE has produced a visual summary on evaluating risk of severe illness or death from sepsis.

1.5 Grading risk

People have the right to be involved in discussions and make informed decisions about their care, as described in NICE's information on making decisions about your care.

Making decisions using NICE guidelines explains how we use words to show the strength (or certainty) of our recommendations, and has information about prescribing medicines (including off-label use), professional guidelines, standards and laws (including on consent and mental capacity), and safeguarding.

1.5.2

Recognise that people with suspected sepsis who are or have recently been pregnant are at:

1.5.3

If people with suspected sepsis who are or have recently been pregnant do not meet any high risk or moderate to high risk criteria, see them as being at low risk of severe illness or death from sepsis. [2016]

Criteria for stratification of risk from sepsis in people who are or have recently been pregnant

Table 1 - Criteria for stratification of risk of severe illness or death from sepsis in people who are or have recently been pregnant
Category High risk criteria Moderate to high risk criteria

History

Objective evidence of new altered mental state

History from patient, friend or relative of new onset of altered behaviour or mental state

History of acute deterioration of functional ability

Impaired immune system (illness or drugs including oral steroids)

Trauma, surgery or invasive procedures in the last 6 weeks

Respiratory

Raised respiratory rate: 25 breaths per minute or more

New need for oxygen (40% FiO2 or more) to maintain saturation more than 92% (or more than 88% in known chronic hypercapnic respiratory failure)

See recommendation 1.4.9 for safety warnings about the use of pulse oximeters

Raised respiratory rate: 21 to 24 breaths per minute

Blood pressure

Systolic blood pressure 90 mmHg or less or systolic blood pressure more than 40mmHg below normal

Systolic blood pressure 91 to 100 mmHg

Circulation and hydration

Raised heart rate: more than 130 beats per minute

Not passed urine in previous 18 hours.

For catheterised patients, passed less than 0.5 ml/kg of urine per hour

Raised heart rate: 100 to 130 beats per minute or new-onset arrhythmia

Not passed urine in the past 12 to 18 hours

For catheterised patients, passed 0.5 ml/kg to 1 ml/kg of urine per hour

Temperature

-

Tympanic temperature less than 36°C

Skin

Mottled or ashen appearance

Cyanosis of skin, lips or tongue

Non-blanching petechial or purpuric rash

For signs and symptoms of meningococcal disease, see the NICE guideline on bacterial meningitis and meningococcal disease.

Signs of potential infection, including redness, swelling or discharge at surgical site or breakdown of wound

This table is also available to download as a visual summary on evaluating risk of severe illness or death in all settings.