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Kidney cancer: diagnosis and management

  • NICE guideline
  • Reference number: NG256
  • Published:  19 March 2026
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Evidence reviews - March 2026

The following documents contain the evidence that was used to develop the 2026 recommendations:

  • Management of localised renal cell carcinoma using partial versus radical nephrectomy
  • Management of localised renal cell carcinoma using non-surgical interventions or active surveillance
  • Management of locally advanced renal cell carcinoma using nephrectomy or stereotactic ablative radiotherapy
  • Information needs
  • Monitoring of untreated renal lesions using active surveillance
  • Follow-up of previously treated renal cell carcinoma
  • Genetic assessment and management of renal cell carcinoma (RCC) associated with heritable RCC syndromes
  • Management of advanced renal cell carcinoma using non-pharmacological interventions
  • CT and MRI for diagnosing renal lesions in adults with suspected renal cell carcinoma
  • Additional imaging tests for differentiating types of renal lesions
  • Renal biopsy
  • Risk prediction tools for localised and locally advanced renal cell carcinoma
  • Risk prediction tools for metastatic renal cell carcinoma

Other supporting evidence

  • Methods
  • Economic analysis report on management of localised renal cell carcinoma using non-surgical interventions or active surveillance
  • Economic model report for follow up and monitoring for previously treated renal cell carcinoma
 

This page was last updated: 19 March 2026

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