Type 2 diabetes in adults: management

Evidence reviews

Evidence for the 2022 recommendations can be found in the evidence review on pharmacological therapies with cardiovascular and other benefits in people with type 2 diabetes, continuous glucose monitoring in adults with type 2 diabetes and periodontal treatment to improve diabetic control in adults with type 1 or type 2 diabetes.

Evidence for the 2021 recommendations can be found in the evidence review on SGLT2 inhibitors for people with chronic kidney disease and type 2 diabetes.

In 2018 we reviewed the evidence for SGLT2 inhibitors and GLP-1 mimetics, and made no new recommendations. See the evidence review on SGLT2 inhibitors and GLP-1 mimetics for more information.

Evidence for the 2009 and 2015 recommendations can be found in the 2015 full guideline on type 2 diabetes in adults, and supporting appendices:

• 2015 full guideline on type 2 diabetes in adults
• Appendix A: Guideline Development Groups & Declarations of Interest 
• Appendix B: Scopes  
• Appendix C: Search strategies and review protocols 
• Appendix D: GRADE tables and meta-analysis result 
• Appendix E: Evidence tables
• Appendix F: Full health economics report 
• Appendix G: NICE guideline CG66 deleted text  
• Appendix H: NICE guideline CG87 deleted text  
• Appendix I: NICE guideline CG87 deleted appendix  
• Appendix J: NMA results and input data  
• Appendix K: WinBUGS code  
• Appendix L: Excluded studies  

See also the 2019 surveillance report on diabetes:

• 2019 surveillance of diabetes (NICE guidelines NG17, NG18, NG19 and NG28)
• Appendix A1: Summary of evidence from surveillance (NG17)  
• Appendix B1: Stakeholder consultation comments table (NG17)
• Appendix A2: Summary of evidence from surveillance (NG28)  
• Appendix B2: Stakeholder consultation comments table (NG28)  
• Appendix A3: Summary of evidence from surveillance (NG18)
• Appendix B3: Stakeholder consultation comments table (NG18)  
• Appendix A4: Summary of evidence from surveillance (NG19)
• Appendix B4: Stakeholder consultation comments table (NG19)