Evidence Review and download supporting evidence. Includes the full guideline if available. Supporting evidence Full guidance Full guideline PDF 2.44 MB 09 December 2015 Appendix A: Scope PDF 1.03 MB 09 December 2015 Appendix B: Declarations of interest PDF 172.85 KB 09 December 2015 Appendix C: Review protocols PDF 277.45 KB 09 December 2015 Appendix D: Clinical article selection PDF 613.02 KB 09 December 2015 Appendix E: Economic article selection PDF 198.18 KB 09 December 2015 Appendix F: Literature search strategies PDF 1021.26 KB 09 December 2015 Appendix G: Clinical evidence tables PDF 420.8 KB 09 December 2015 Appendix H: Economic evidence tables PDF 123.58 KB 09 December 2015 Appendix I: GRADE tables PDF 289.11 KB 09 December 2015 Appendix J: Forest plots PDF 241.92 KB 09 December 2015 Appendix K: Excluded clinical studies PDF 358.9 KB 09 December 2015 Appendix L: Excluded economic studies PDF 122.74 KB 09 December 2015 Appendix M: Cost sensitivity analysis PDF 332.57 KB 09 December 2015 Appendix N: Research recommendations PDF 165.89 KB 09 December 2015 Appendix O: NICE technical team PDF 123.88 KB 09 December 2015