Update information

June 2018: We reviewed the evidence on response assessment after chemoradiotherapy and added new recommendations and recommendations for research.

Recommendations are marked as [2018] or [2016].

[2018] indicates that the evidence was reviewed and the recommendation added in 2018.

[2016] indicates that the evidence was last reviewed in 2016.

Minor changes since publication

December 2025: We added links to relevant technology appraisal guidance in the section on systemic anticancer therapy for squamous cell carcinoma of the head and neck airways. We also simplified the guideline by removing recommendations on general principles of care that are covered in other NICE guidelines. 

ISBN: 978‑1‑4731‑1661‑0