Suggested remit: To appraise the clinical and cost effectiveness of esketamine within its marketing authorisation for the treatment of major depressive disorder.
 
Status Proposed
Process STA 2018
ID number 1414

Provisional Schedule

Committee meeting 07 January 2020
Expected publication 18 March 2020

Project Team

Project lead Gemma Barnacle

Email enquiries

Consultees

Companies sponsors Janssen (esketamine)
Others Department of Health and Social Care
  NHS England
  Welsh Government
Patient carer groups SANE
Professional groups British Association for Psychopharmacology
  Royal College of Physicians

Commentators

Comparator companies Accord Healthcare (amitriptyline, citalopram, duloxetine, escitalopram, imipramine, lofepramine, mirtazapine, fluoxetine, paroxetine, quetiapine, sertraline and venlafaxine) (Confidentiality agreement not signed, not participating)
  Amneal Pharma Europe (duloxetine, paroxetine) (Confidentiality agreement not signed, not participating)
  Arristo Pharma (quetiapine) (Confidentiality agreement not signed, not participating)
  AstraZeneca (quetiapine) (Confidentiality agreement not signed, not participating)
  Aurobindo Pharma (citalopram, duloxetine, escitalopram, fluoxetine, mirtazapine, paroxetine, quetiapine, sertraline and venlafaxine) (Confidentiality agreement not signed, not participating)
  Chiesi (venlafaxine) (Confidentiality agreement not signed, not participating)
  Consilient Health (duloxetine, escitalopram, quetiapine and venlafaxine) (Confidentiality agreement not signed, not participating)
  Creo Pharma (lofepramine and trazodone)
  Dexcel Pharma (venlafaxine) (Confidentiality agreement not signed, not participating)
  Dr Reddys Labs (duloxetine, fluoxetine and sertraline) (Confidentiality agreement not signed, not participating)
  Fontus heath (quetiapine) (Confidentiality agreement not signed, not participating)
  GlaxoSmithKline (paroxetine) (Confidentiality agreement not signed, not participating)
  HBS Healthcare (duloxetine) (Confidentiality agreement not signed, not participating)
  King Pharmaceuticals (nortriptyline) (Confidentiality agreement not signed, not participating)
  Kyowa Kirin (phenelzine) (Confidentiality agreement not signed, not participating)
  Lilly UK (duloxetine and fluoxetine) (Confidentiality agreement not signed, not participating)
  Lundbeck (citalopram, escitalopram, vortioxetine)
  Lupin (sertraline) (Confidentiality agreement not signed, not participating)
  Marlborough (doxepin) (Confidentiality agreement not signed, not participating)
  Merck Sharp & Dohme (mirtazapine) (Confidentiality agreement not signed, not participating)
  Mylan (citalopram, clomipramine, escitalopram, fluoxetine, fluvoxamine, lofepramine, mianserin, mirtazapine, paroxetine, quetiapine, trazodone and venlafaxine) (Confidentiality agreement not signed, not participating)
  Par Laboratories Europe (fluoxetine) (Confidentiality agreement not signed, not participating)
  Pfizer (reboxetine, sertraline and venlafaxine) (Confidentiality agreement not signed, not participating)
  Rivopharm (citalopram, trazodone) (Confidentiality agreement not signed, not participating)
  Sandoz (citalopram, paroxetine and quetiapine) (Confidentiality agreement not signed, not participating)
  Servier (agomelatine) (Confidentiality agreement not signed, not participating)
  Sun Pharmaceuticals (sertraline and venlafaxine) (Confidentiality agreement not signed, not participating)
  Teva UK (amitriptyline, citalopram, clomipramine, fluoxetine, fluvoxamine, imipramine, lofepramine, mianserin, mirtazapine, paroxetine, sertraline, trazodone and venlafaxine) (Confidentiality agreement not signed, not participating)
  Wockhardt (amitriptyline, fluoxetine, fluvoxamine, mirtazapine and venlafaxine) (Confidentiality agreement not signed, not participating)
  Zentiva (citalopram, duloxetine, escitalopram, quetiapine, trazodone and trimipramine) (Confidentiality agreement not signed, not participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Scottish Medicines Consortium
  Welsh Health Specialised Services Committee

Timeline

Key events during the development of the guidance:

Date Update
01 May 2019 Invitation to participate
17 September 2018 (14:00) Scoping workshop (London)
25 July 2018 - 22 August 2018 Consultation on suggested remit, draft scope and provisional matrix of consultees and commentators

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance