Information for the public

Niraparib (Zejula) is available on the NHS. It is a possible maintenance treatment for advanced epithelial (FIGO stages 3 and 4) high-grade ovarian, fallopian tube or primary peritoneal cancer in adults if:

  • the cancer responded to first-line platinum-based chemotherapy
  • the person did not have or could not tolerate bevacizumab as part of first-line induction chemotherapy.

Lines of treatment are a sequence of treatments, starting with the most suitable option and moving to alternatives if the first does not work or the condition gets worse. Each line can be a single drug or a combination of drugs.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. See our webpage on shared decision making.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS webpage on ovarian cancer may be a good place to find out more.

These organisations can give you advice and support:

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

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