Information for the public

Seladelpar (Livdelzi) is available on the NHS. It is a possible treatment for primary biliary cholangitis, including associated pruritus (itchy skin) in adults. It can be used:

  • with ursodeoxycholic acid (UDCA), if UDCA alone has not worked well enough, or
  • alone, if UDCA cannot be tolerated.

If you are not eligible for seladelpar but are already having it, you should be able to continue until you and your healthcare professional decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. See our webpage on shared decision making.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS webpage on primary biliary cholangitis may be a good place to find out more.

PBC Foundation (0131 556 6811) can give you advice and support.

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

ISBN: 978-1-4731-9570-7

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