Resource impact summary report
Resource impact summary report
Guidance recommendation(s)
Financial and capacity resource impact
The key drivers of resource impact are that:
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The treatment duration of cemiplimab is longer than comparator treatments.
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The number of administrations in each cycle is less than comparator treatments.
The company has a commercial arrangement. This makes cemiplimab available to the NHS at a discount.
The payment mechanism for the technology is determined by the responsible commissioner and depends on whether the technology is classified as high cost.
Eligible population for cemiplimab
The eligible population is estimated to be around 90 people. This is based on the high proportion of people who are expected to have pembrolizumab as part of their first-line therapy and would therefore be ineligible for cemiplimab at second line. Because the population is small, we have not produced a resource impact template.
Treatment options for the eligible population
The comparator treatments for the eligible population are single-agent chemotherapies.
Cemiplimab, paclitaxel and gemcitabine are all administered via IV infusion but paclitaxel and gemcitabine both have two administrations per cycle.
Key information
| Time from publication to routine commissioning funding |
90 days |
|---|---|
| Programme budgeting category |
02G cancers and tumours, gynaecological |
| Commissioner |
NHS England |
| Providers |
NHS hospital trusts |
| Pathway position |
2nd line |
About this resource impact summary report
This resource impact summary report accompanies the NICE technology appraisal guidance on cemiplimab for treating recurrent or metastatic cervical cancer that has progressed on or after platinum-based chemotherapy and should be read with it.
ISBN: 978-1-4731-9607-0
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