6 Recommendation for further research

6 Recommendation for further research

6.1 The Committee identified a need for RCTs comparing alternative chemotherapy regimens in MPM. Specifically, the Committee recommended that trials be conducted in which pemetrexed plus cisplatin is compared with treatments that are currently commonly used in clinical practice in England and Wales in order to determine its relative effectiveness. The Committee also recommended that comparative trials of pemetrexed plus cisplatin versus other promising treatments be conducted.