6 Recommendations for further research

6 Recommendations for further research

6.1 More trials of apixaban compared with other LMWHs in total hip and knee replacement would decrease the uncertainty of the clinical and cost effectiveness of these treatments. Trials directly comparing apixaban with rivaroxaban, dabigatran etexilate and fondaparinux would strengthen the evidence base for these comparisons.

  • National Institute for Health and Care Excellence (NICE)