Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapy

Review proposal consultation

Stakeholder matrix (PDF 99 KB)

Review proposal paper (PDF 222 KB)

Colorectal cancer (metastatic) - aflibercept: equality impact assessment form - guidance development (PDF 22 KB)

Colorectal cancer (metastatic) - aflibercept: final appraisal determination information

Colorectal cancer (metastatic) - aflibercept: final appraisal determination (PDF 249 KB)

Colorectal cancer (metastatic) - aflibercept: evaluation report information

Colorectal cancer (metastatic) - aflibercept: evaluation report (PDF 509 KB)

Colorectal cancer (metastatic) - aflibercept: appeal

Colorectal cancer (metastatic) - aflibercept: appeal decision (PDF 280 KB)

Colorectal cancer (metastatic) - aflibercept: appeal announcement information

Colorectal cancer (metastatic) - aflibercept: Sanofi appeal

Colorectal cancer (metastatic) - aflibercept: Sanofi appeal - appeal letter (PDF 893 KB)

Colorectal cancer (metastatic) - aflibercept: Sanofi appeal - initial scrutiny letter (PDF 94 KB)

Colorectal cancer (metastatic) - aflibercept: Sanofi appeal - response to initial scrutiny (PDF 267 KB)

Colorectal cancer (metastatic) - aflibercept: Sanofi appeal - final scrutiny letter (PDF 142 KB)

Colorectal cancer (metastatic) - aflibercept: Beating Bowel Cancer appeal information

Colorectal cancer (metastatic) - aflibercept: Beating Bowel Cancer appeal - appeal letter (PDF 44 KB)

Colorectal cancer (metastatic) - aflibercept: Beating Bowel Cancer appeal - initial scrutiny letter (PDF 37 KB)

Colorectal cancer (metastatic) - aflibercept: Beating Bowel Cancer appeal - final scrutiny letter (PDF 18 KB)

Colorectal cancer (metastatic) - aflibercept: register to attend the appeal information

Colorectal cancer (metastatic) - aflibercept: notice of appeal information

Colorectal cancer (metastatic) - aflibercept: appraisal consultation

Colorectal cancer (metastatic) - aflibercept: appraisal consultation document information

Colorectal cancer (metastatic) - aflibercept: evaluation report information

Colorectal cancer (metastatic) - aflibercept: evaluation report (PDF 4.99 MB)

Evidence Review Group report - Erratum (PDF 72 KB)

Colorectal cancer (metastatic) - aflibercept: Appendix C - final scope (PDF 27 KB)

Colorectal cancer (metastatic) - aflibercept: Appendix B - final matrix (PDF 36 KB)

Colorectal cancer (metastatic) - aflibercept: Appendix D - response to comments on the draft scope and provisional matrix (PDF 93 KB)

Colorectal cancer (metastatic) - aflibercept: Appendix B - draft scope for consultation (pre-referral) - September 2011 (PDF 103 KB)

Colorectal cancer (metastatic) - aflibercept: Appendix C - provisional matrix (pre-referral) - September 2011 (PDF 106 KB)