The condition and the treatment
Heart failure means your heart cannot efficiently pump blood around the body, usually because the heart muscle has been damaged or is too weak to work properly. 'Chronic heart failure' describes heart failure as a long-term condition.
People with heart failure may feel breathless and very tired, although these symptoms can be caused by many other things. Standard treatments for heart failure include drugs called angiotensin-converting enzyme (or ACE) inhibitors, and angiotensin II receptor blockers (or ARBs).
Sacubitril valsartan (Entresto) is a single treatment that combines an ARB and a drug called a neprilysin inhibitor to help treat chronic heart failure.
NHS Choices may be a good place to find out more.