6 Recommendations for research

Further research is recommended to resolve uncertainties about the clinical effectiveness of degarelix compared with LHRH agonists such as leuprorelin, goserelin and triptorelin for treating advanced hormone-dependent prostate cancer, particularly in subgroups of people with pre-existing cardiovascular disease, people with skeletal (including spinal) metastases and people with impending ureteric and urethral obstruction. Research should be planned as part of well-conducted randomised clinical trials.

  • National Institute for Health and Care Excellence (NICE)