2 The technologies

2 The technologies

2.1 The technologies being considered in this appraisal can be used at any point in the treatment pathway, within their marketing authorisations. Costs may vary in different settings because of negotiated procurement discounts.

Drug, dosage form and dosage

Indication

Price

Alendronic acid (generic) tablets, 10 mg once a day

  • Treating postmenopausal osteoporosis

  • Preventing and treating corticosteroid-induced osteoporosis in postmenopausal women not receiving hormone replacement therapy

  • Treating osteoporosis in men

28‑tablet pack = £1.69

Alendronic acid (generic) tablets, 70 mg once a week

  • Treating postmenopausal osteoporosis

4‑tablet pack = £0.72

Alendronic acid (generic) oral solution, 70 mg/100 ml once a week

4 × 100 ml = £27.36

Ibandronic acid (generic) tablets, 150 mg once a month

  • Treating postmenopausal osteoporosis

1‑tablet pack = £1.13

Ibandronic acid (generic) injection, 3 mg/3 ml once every 3 months

  • Treating postmenopausal osteoporosis

3‑ml prefilled syringe = £10.27*

Risedronate sodium (generic) tablets, 5 mg once a day

  • Treating postmenopausal osteoporosis to reduce risk of vertebral or hip fractures

  • Preventing osteoporosis (including corticosteroid-induced osteoporosis) in postmenopausal women

28‑tablet pack = £8.60*

Risedronate sodium (generic) tablets, 35 mg once a week

  • Treating postmenopausal osteoporosis to reduce risk of vertebral or hip fractures

  • Treating osteoporosis in men at high risk of fractures

4‑tablet pack = £0.85

Zoledronic acid

(generic) intravenous infusion, 50 micrograms/ml once a year

  • Treating postmenopausal osteoporosis and osteoporosis in men (including corticosteroid-induced osteoporosis)

100‑ml solution for infusion bag = £7.36*

Prices based on National drug tariff

* Price based on eMIT database (data from 12-month period to end December 2015).

  • National Institute for Health and Care Excellence (NICE)