2 Information about chondrosphere

2 Information about chondrosphere

Information about chondrosphere

Marketing authorisation

Chondrosphere (Spherox, Co.don) is indicated for the 'repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Repair Society [ICRS] grade III or IV) with defect sizes up to 10 cm2 in adults'.

Dosage in the marketing authorisation

10 to 70 spheroids are applied per square centimetre of defect.


£10,000 per culture per patient, including cell costs and transportation. Costs may vary in different settings because of negotiated procurement discounts.

  • National Institute for Health and Care Excellence (NICE)