Rivaroxaban (Xarelto) with aspirin is available on the NHS. It is a possible treatment for preventing atherothrombotic events (such as stroke or heart attack) in adults who are at high risk because they have:

  • peripheral artery disease or
  • coronary artery disease and they:
    • are 65 or older, or
    • have atherosclerosis (fatty deposits) in at least 2 arteries, or
    • have at least 2 extra risk factors such as smoking, diabetes, certain types of kidney problem, heart failure, or they’ve had a type of stroke called a non-lacunar ischaemic stroke.

Rivaroxaban with aspirin may increase the risk of bleeding. So your risk of bleeding needs to be assessed before deciding whether to start treatment.

If you are not eligible for rivaroxaban but are already taking it, you should be able to continue until you and your doctor decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. Read more about making decisions about your care.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

These organisations can give you advice and support:

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

ISBN: 978-1-4731-3510-9


This page was last updated: 17 October 2019